Difference between revisions of "Exercise"

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The fifth intervention to reverse mild Alzheimer's in the [[Bredesen Protocol]] is:
'''Goal''': Exercise


:'''Goal''': Exercise
'''Approach''': 30-60 minutes per day, 4-6 days per week.


:'''Approach''': 30-60 minutes per day, 4-6 days per week.


== How to work out your target average heart rate? ==
Dr Bredesen emphasizes exercise in his protocol to:
* reduce, even reverse, hippocampal atrophy in the brain 
* Increase BDNF (Brain Derived Neurotrophic Factor) [[https://wiki.apoe4.info/wiki/BDNF |BDNF ]] 
* Work hand in hand with diet and fasting to create ketones as an alternative source of energy for the brain
 


Dr. Bredesen also stated that his protocol recommends at least 30 minutes of exercise, at least 4 days per week [3][4][5]. He recommended that the target heartrate should be around 70% of your average maximum heartrate for your age, as shown in this table [5]:
Dr. Bredesen also stated that his protocol recommends at least 30 minutes of exercise, at least 4 days per week [3][4][5]. He recommended that the target heartrate should be around 70% of your average maximum heartrate for your age, as shown in this table [5]:


{| class="wikitable"
{| class="wikitable"
|-
|-
! Age !! Target HR Zone 50-85% !! Average Maximum Heart Rate, 100%
! Age !! Target Heart Rate Zone 50-85% !! Average Maximum Heart Rate, 100%
|-
|-
| 20 years || 100-170 beats per minute || 200 beats per minute
| 20 years || 100-170 beats per minute || 200 beats per minute
Line 33: Line 37:
| 70 years || 75-128 beats per minute || 150 beats per minute
| 70 years || 75-128 beats per minute || 150 beats per minute
|}
|}


There are many fitness products that will track your average heartrate for you during an exercise session.
There are many fitness products that will track your average heartrate for you during an exercise session.


== See Also ==


For more see:
* Check out [[Exercise - Types, Lengths, and Benefits]]  for more detailed discussion on different types of exercise with benefits and risks for ApoE4s, beyond the recommendations of Dr Bredesen's protocol 
* [https://en.wikipedia.org/wiki/Neurobiological_effects_of_physical_exercise#Structural_growth Wikipedia: Neurobiological Effects of Physical Exercise].
* [https://en.wikipedia.org/wiki/Neurobiological_effects_of_physical_exercise#Structural_growth Wikipedia: Neurobiological Effects of Physical Exercise].
* [http://en.wikipedia.org/wiki/Hippocampus Wikipedia: Hippocampus].
* [http://en.wikipedia.org/wiki/Hippocampus Wikipedia: Hippocampus].


== References ==
 
'''References'''


* [1] [http://www.ncbi.nlm.nih.gov/pubmed/24938502 Rivastigmine transdermal patch and physical exercises for Alzheimer's disease: a randomized clinical trial]
* [1] [http://www.ncbi.nlm.nih.gov/pubmed/24938502 Rivastigmine transdermal patch and physical exercises for Alzheimer's disease: a randomized clinical trial]
* [2] [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005962/ Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease]
* [2] [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005962/ Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease]
* [3] [https://www.youtube.com/watch?v=2HFs0GyIR2M YouTube: "Dale Bredesen Alzheimer's QnA"]: At 8 minutes and 45 seconds into the video, he answers a questions about the optimal amount of exercise.
* [3] [https://www.youtube.com/watch?v=2HFs0GyIR2M YouTube: "Dale Bredesen Alzheimer's QnA"]: At 8 minutes and 45 seconds into the video, he answers a question about the optimal amount of exercise.
* [4] Google "maximum  heart rate for your age" to get a table for the maximum heartrate for your age.
* [4] Google "maximum  heart rate for your age" to get a table for the maximum heartrate for your age.
* [5] [http://www.heart.org/HEARTORG/HealthyLiving/PhysicalActivity/FitnessBasics/Target-Heart-Rates_UCM_434341_Article.jsp#.V-kwnCSok3g American Heart Association: Target Heart Rates].
* [5] [http://www.heart.org/HEARTORG/HealthyLiving/PhysicalActivity/FitnessBasics/Target-Heart-Rates_UCM_434341_Article.jsp#.V-kwnCSok3g American Heart Association: Target Heart Rates].


== Next Intervention ==


The next intervention in the [[Bredesen Protocol]] is [[Brain stimulation]].
-----
 
'''Return to [[Bredesen_Protocol#Lifestyle_Strategies|Lifestyle Strategies]].'''

Revision as of 09:07, 4 March 2018

Goal: Exercise

Approach: 30-60 minutes per day, 4-6 days per week.


Dr Bredesen emphasizes exercise in his protocol to:

  • reduce, even reverse, hippocampal atrophy in the brain
  • Increase BDNF (Brain Derived Neurotrophic Factor) [|BDNF ]
  • Work hand in hand with diet and fasting to create ketones as an alternative source of energy for the brain


Dr. Bredesen also stated that his protocol recommends at least 30 minutes of exercise, at least 4 days per week [3][4][5]. He recommended that the target heartrate should be around 70% of your average maximum heartrate for your age, as shown in this table [5]:


Age Target Heart Rate Zone 50-85% Average Maximum Heart Rate, 100%
20 years 100-170 beats per minute 200 beats per minute
30 years 95-162 beats per minute 190 beats per minute
35 years 93-157 beats per minute 185 beats per minute
40 years 90-153 beats per minute 180 beats per minute
45 years 88-149 beats per minute 175 beats per minute
50 years 85-145 beats per minute 170 beats per minute
55 years 83-140 beats per minute 165 beats per minute
60 years 80-136 beats per minute 160 beats per minute
65 years 78-132 beats per minute 155 beats per minute
70 years 75-128 beats per minute 150 beats per minute


There are many fitness products that will track your average heartrate for you during an exercise session.


For more see:


References



Return to Lifestyle Strategies.