Increase SirT1 function
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The twenty third intervention to reverse mild Alzheimer's in the Bredesen Protocol is:
- Goal: Increase SirT1 function
- Approach: Resveratrol
- References: Neuroprotective Sirtuin ratio reversed by ApoE4
SirT1 is an enzyme that deacetylates proteins that contribute to cellular regulation (reaction to stressors, longevity).
Resveratrol is produced naturally by several plants in response to injury or when the plant is under attack by pathogens such as bacteria or fungi.
The next intervention in the Bredesen Protocol is Exclude heavy metal toxicity.